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Invitrogen
ATXN1L Polyclonal Antibody
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产品信息
PA5-66532
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: HPGIHYPPLHY AQLPSTSLQF IGSPYSLPYA VPPNFLPSPL LSPSANLATS HLPHFVPYAS LLAEGATPP
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 93%.
靶标信息
Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (PubMed:21475249). Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ataxin 1-like; Ataxin-1-like; Brother of ataxin-1; Brother of ATXN1
基因别名: ATXN1L; BOAT; BOAT1
UniProt ID: (Human) P0C7T5
Entrez Gene ID: (Human) 342371
