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Invitrogen
AXUD1 Polyclonal Antibody
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产品信息
PA5-100400
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CSRNP1(Accession Q96S65), corresponding to amino acid residues S486-H536.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total AXUD1.
靶标信息
Axin, an important regulator of beta-catenin, is frequently mutated in human hepatocellular carcinomas (HCCs), and transduction of the wild-type Axin gene (AXIN1) induces apoptosis in HCC cells as well as in colon cancer cells. A novel gene, AXUD1 (AXIN1 up-regulated), has enhanced expression in response to exogenously expressed AXIN1. It is expressed in all human tissues examined, most abundantly in lung, placenta, skeletal muscle, pancreas and leukocytes. Data suggests that AXUD1 may have a tumor-suppressor function in those organs.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Axin-1 up-regulated gene 1 protein; AXIN1 up-regulated 1; CSRNP-1; Cysteine/serine-rich nuclear protein 1; DKFZp566F164; Protein URAX1; TAIP-3; TGF-beta induced apoptosis protein 3; TGF-beta-induced apoptosis protein 3; URAX1 protein
基因别名: 4931429D10Rik; AXUD1; CSRNP-1; CSRNP1; FAM130B; TAIP-3; TAIP3; URAX1
UniProt ID: (Human) Q96S65, (Mouse) P59054
Entrez Gene ID: (Human) 64651, (Rat) 363165, (Mouse) 215418
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
post-embryonic development
positive regulation of transcription from RNA polymerase II promoter
platelet-derived growth factor receptor signaling pathway
skeletal system morphogenesis
palate development
face morphogenesis
transcription, DNA-templated
apoptotic process
