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Invitrogen
AZGP1 Monoclonal Antibody (C5)
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AZGP1 Antibody (MA5-41545) in WB
Western blot analysis of AZGP1 using AZGP1 Monoclonal Antibody (C5) (Product # MA5-41545) at a dilution of 0.2 µg/mL. Lane 1: Rat Prostate lysate; Lane 2: Rat Lung lysate; Lane 3: Rat Heart lysate. Secondary antibody used is HRP-Goat anti-Mouse IgG polyclonal antibody at a dilution of 0.2 µg/mL.
产品信息
MA5-41545
产品规格
种属反应
Rat
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
C5
抗原
Recombinant protein Alpha-2-Glycoprotein 1, Zinc Binding. The antigen corresponds to amino acid range 18-296 of the target protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Alpha-2-glycoprotein 1, zinc-binding (AZGP1) is a gene encoding a protein that belongs to the immunoglobulin superfamily. This protein is abundant in various body fluids, such as blood plasma and milk, and is involved in lipid mobilization. AZGP1 is expressed in numerous tissues, including the liver, prostate, and adipose tissue, where it plays a significant role in the regulation of lipid metabolism and adipocyte function. It acts as an adipokine, influencing the breakdown and mobilization of fats, thereby contributing to energy homeostasis. In cancer research, AZGP1 has been highlighted for its potential as a prognostic biomarker, particularly in prostate and breast cancer, where lower expression levels are often associated with poor prognosis. Recent studies have also linked AZGP1 to cachexia, an extreme form of weight loss and muscle wasting, by promoting lipid mobilization in adipose tissue and influencing systemic catabolic states. Due to its multifaceted roles in lipid metabolism and disease processes, AZGP1 is considered a promising target for therapeutic interventions in metabolic and cancer-related disorders.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha-2 - glycoprotein 1 zinc; alpha-2 - glycoprotein 1, zinc; alpha-2-glycoprotein 1, zinc; Zinc a 2 glycoprotein; Zinc a2glycoprotein; Zinc alpha2glycoprotein; Zinc α 2 glycoprotein; Zinc α2glycoprotein; zinc-alpha-2-glycoprotein; Zn - alpha2 - glycoprotein; Zn a 2 glycoprotein; Zn a 2 GP; Zn alpha 2 glycoprotein; Zn alpha 2 GP; Zn α 2 glycoprotein; Zn α 2 GP; zn-alpha-2-glycoprotein; zn-alpha-2-GP
基因别名: ZA2GA; Zna2gp
Entrez Gene ID: (Rat) 25294
