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Abnova
Acox1 Recombinant Rabbit Monoclonal Antibody
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产品信息
RAB01632
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Recombinant protein corresponding to mouse ACOX1.
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
50mM tris glycine, pH 7.4, with 150mM NaCl, 40% glycerol, 0.05% BSA
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AOX; Palmitoyl-CoA oxidase; Peroxisomal acyl-coenzyme A oxidase 1; Peroxisomal fatty acyl-CoA oxidase; peroxisomal fatty acyl-coenzyme A oxidase; peroxisomal straight-chain Acyl-CoA oxidase; Straight-chain acyl-CoA oxidase
基因别名: Acox; Acox1; AOX; D130055E20Rik; Paox
UniProt ID: (Mouse) Q9R0H0
Entrez Gene ID: (Mouse) 11430
acyl-CoA dehydrogenase activity
acyl-CoA oxidase activity
receptor binding
fatty acid binding
palmitoyl-CoA oxidase activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
PDZ domain binding
protein N-terminus binding
flavin adenine dinucleotide binding
FAD binding
oxidoreductase
very long-chain fatty acid metabolic process
generation of precursor metabolites and energy
lipid metabolic process
fatty acid metabolic process
fatty acid beta-oxidation
prostaglandin metabolic process
spermatogenesis
metabolic process
peroxisome fission
fatty acid oxidation
fatty acid beta-oxidation using acyl-CoA oxidase
lipid homeostasis
oxidation-reduction process
positive regulation of cholesterol homeostasis
