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Invitrogen
Actin Recombinant Rabbit Monoclonal Antibody (HL2372)
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Actin Antibody (MA5-56585) in ICC/IF
Immunocytochemistry analysis of Actin using Actin Recombinant Monoclonal Antibody (Product # MA5-56585) in HeLa cells fixed in ice-cold MeOH for 5 min at cytoskeleton. Green: Actin stained by Actin antibody at a dilution of 1:1,000. Blue: Fluoroshield with DAPI.
产品信息
MA5-56585
应用
建议稀释比
已发表文章
产品规格
种属反应
Dog,
Fruit fly,
Cat,
Human,
Mouse,
Non-human primate,
Rabbit,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL2372
抗原
Recombinant fragment of human Actin.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
Actin exists as a ubiquitous protein involved with filament formation that make up large portions of the cytoskeleton. Actin filaments interact with myosin to assist in muscle contraction as well as aiding in cell motility and cytokinesis. In vertebrates there are three groups of actin isoforms: alpha, beta and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exists in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5C actin; Act5C-PA; Act5C-PB; Act5C-PC; Act5C-PD; Act5C-PE; actin; actin 5 C; actin 5c; actin A1; actin alpha 1; actin alpha cardiac; actin alpha cardiac 1; actin, alpha 1, skeletal muscle; actin, alpha 2, smooth muscle, aorta; Actin, alpha cardiac muscle 1; Actin, alpha skeletal muscle; actin, alpha, cardiac 1; actin, alpha, vascular smooth muscle; Actin, aortic smooth muscle; actin, beta; Actin, cytoplasmic 1; Actin, cytoplasmic 2; actin, gamma 2, smooth muscle, enteric; actin, gamma, cytoplasmic 1; Actin, gamma-enteric smooth muscle; Actin-5C; actin-like protein; actin5C; alpha-actin cardiac; Alpha-actin-1; Alpha-actin-2; Alpha-actin-3; Alpha-cardiac actin; alpha-sma; alpha-smooth muscle actin; alphac-actin; anon-fast-evolving-2D2; Atcb; beta cytoskeletal actin; Beta-actin; beta-actin FE-3; cardiac actin; Cell growth-inhibiting gene 46 protein; cellular cytoskeletal beta-actin; CG4027-PA; CG4027-PB; CG4027-PC; CG4027-PD; CG4027-PE; cytoplasmic beta-actin; cytoskeletal gamma-actin; deafness, autosomal dominant 20; deafness, autosomal dominant 26; Dm-actin5C; epididymis luminal protein 176; F-actin; G-actin; gamma non-muscle actin; Gamma-2-actin; Gamma-actin; gamma-enteric smooth muscle actin; nemaline myopathy type 3; pan actin; PS1TP5-binding protein 1; RE02927p; RP5-1068B5.2; smooth muscle alpha-actin; Smooth muscle gamma-actin; unnamed protein product
基因别名: 0610041G09Rik; A; a-SMA; A4V404_DROME; AA959943; AAT6; Ac5C; ACT; act 5C; Act-4; ACT-5; Act-5C; ACT1_DROME; Act4; Act5; ACT5C; ACTA; Acta-2; ACTA1; ACTA2; ACTA3; ACTB; ACTC; Actc-1; ACTC1; ACTE; ACTG; ACTG1; ACTG2; ACTGE; Actin; Actin/BAP47; Actin5C; Actl; ACTL3; Acts; ACTSA; ACTSG; Actsk-1; ACTVS; Actx; AL023024; alphaSMA; anon-EST:fe2D2; ArpA; ASD5; ASMA; BAP47; beta-actin; beta-actin/Bap47; BRWS1; BRWS2; CFTD; CFTD1; CFTDM; CG4027; chrX:5748184..5748304; CMD1R; CMH11; cyt5C; DFNA20; DFNA26; Dmel\CG4027; Dmel_CG4027; E430023M04Rik; E51; F-actin; G-actin; GIG46; HEL-176; l(1)G0009; l(1)G0010; l(1)G0025; l(1)G0079; l(1)G0117; l(1)G0177; l(1)G0245; l(1)G0330; l(1)G0420; l(1)G0486; LVNC4; M32055; MPFD; MYMY5; NEM1; NEM2; NEM3; PS1TP5BP1; SHPM; SMalphaA; SMGA; T11; VSCM
UniProt ID: (Human) P68133, (Rabbit) P62740, (Human) P62736, (Rabbit) P29751, (Human) P60709, (Dog) O18840, (Human) P68032, (Human) P63261, (Human) P63267, (Fruit fly) P10987, (Mouse) P68134, (Rat) P68136, (Rat) P62738, (Mouse) P62737, (Rat) P60711, (Mouse) P60710, (Rat) P68035, (Mouse) P68033, (Mouse) P63260, (Rat) P63259, (Mouse) P63268, (Rat) P63269
Entrez Gene ID: (Human) 58, (Rabbit) 100009506, (Dog) 488984, (Dog) 477587, (Rabbit) 100009271, (Human) 59, (Rabbit) 100009272, (Cat) 100144392, (Human) 60, (Dog) 403580, (Dog) 478250, (Human) 70, (Rabbit) 100340339, (Human) 71, (Dog) 475923, (Human) 72, (Rabbit) 100350318, (Dog) 475792, (Fruit fly) 31521, (Mouse) 11459, (Rat) 29437, (Rat) 81633, (Mouse) 11475, (Rat) 81822, (Mouse) 11461, (Rat) 29275, (Mouse) 11464, (Mouse) 11465, (Rat) 287876, (Mouse) 11468, (Rat) 25365
structural constituent of cytoskeleton
protein binding
ATP binding
myosin binding
ADP binding
protein kinase binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
kinesin binding
Tat protein binding
nucleosomal DNA binding
identical protein binding
nitric-oxide synthase binding
ATPase activity
ubiquitin protein ligase binding
nucleotide binding
molecular_function
actin and actin related protein
actin or actin-binding cytoskeletal protein
cytoskeletal protein
muscle contraction
response to mechanical stimulus
response to extracellular stimulus
response to lithium ion
positive regulation of gene expression
cell growth
muscle filament sliding
skeletal muscle thin filament assembly
skeletal muscle fiber adaptation
response to steroid hormone
skeletal muscle fiber development
mesenchyme migration
regulation of blood pressure
response to virus
vascular smooth muscle contraction
glomerular mesangial cell development
retina homeostasis
movement of cell or subcellular component
cytoskeleton organization
substantia nigra development
cell junction assembly
Fc-gamma receptor signaling pathway involved in phagocytosis
ATP-dependent chromatin remodeling
positive regulation of gene expression, epigenetic
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
platelet aggregation
postsynaptic actin cytoskeleton organization
apoptotic process
actin filament-based movement
actomyosin structure organization
actin-myosin filament sliding
response to drug
negative regulation of apoptotic process
response to ethanol
cardiac myofibril assembly
cardiac muscle tissue morphogenesis
heart contraction
cardiac muscle contraction
sarcomere organization
mitotic cytokinesis
chromatin remodeling
sperm individualization
maintenance of protein location in cell
tube formation
axonogenesis
retina development in camera-type eye
cellular response to electrical stimulus
metabolic process
actin-mediated cell contraction
response to calcium ion
biological_process
