Search Thermo Fisher Scientific
Recommended positive controls: NIH-3T3.
Predicted reactivity: Mouse (84%), Rat (85%), Chimpanzee (99%), Bovine (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: actin-like 7-alpha; actin-like 7A; Actin-like protein 7A; actin-like Tact2; Actin-like-7-alpha; t-actin 2; T-actin-2; testicular secretory protein Li 3; Testis-specific actin-2
基因别名: ACTL7A; Tact2
UniProt ID: (Human) Q9Y615, (Mouse) Q9QY84
Entrez Gene ID: (Human) 10881, (Mouse) 11470
分子生物学功能: actin and actin related protein actin or actin-binding cytoskeletal protein cytoskeletal protein