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Invitrogen
Actin-like 8 Polyclonal Antibody
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产品信息
PA5-21788
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human ACTL8. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.71 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Actin-like protein 8 (ACTL8), also known as Cancer/Testis Antigen 57 (CT57), is part of the cancer/testis antigen (CTA) family. It is primarily expressed in the testes but aberrantly overexpressed in various cancers, including lung adenocarcinoma, endometrial cancer, and colorectal cancer. ACTL8's overexpression is associated with enhanced cell mobility, proliferation, and colony formation, contributing to tumor growth and poor prognosis. The gene is believed to play a critical role in oncogenesis and is being investigated as a potential therapeutic target due to its involvement in tumorigenic processes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: actin like protein; actin-like 8; Actin-like protein 8; Cancer/testis antigen 57; CT57
基因别名: ACTL8; CT57
UniProt ID: (Human) Q9H568
Entrez Gene ID: (Human) 81569
