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Alomone Labs, LTD
Adenylate Cyclase 3 (AC3) (extracellular) Polyclonal Antibody
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Adenylate Cyclase 3 (AC3) (extracellular) Antibody (AAR-043-200UL) in ICC/IF
Expression of Adenylate cyclase type IIIin rat U-87 MG cells - Cell surface detection of Adenylate cyclase type III in intact living rat U-87 MG cells. A. Extracellular staining of cells using Anti-Adenylate Cyclase 3 (AC3) (extracellular) Antibody (#AAR-043), (1:50) followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody (red). B. Merge of A with live view of the cells.
产品信息
AAR-043-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)KHVADEMLKDMKKDE, corresponding to amino acid residues 285-299 of rat ADCY3, 3rd extracellular loop
偶联物
形式
Lyophilized
浓度
0.85 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
靶标信息
This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AC-III; AC3; Adenylate cyclase type 3; Adenylate cyclase type III; Adenylate cyclase, olfactive type; Adenylyl cyclase 3; adenylyl cyclase, type III; ATP pyrophosphate-lyase 3; type III adenylyl cyclase
基因别名: AC-III; AC3; ADCY3; KIAA0511; mKIAA0511
UniProt ID: (Human) O60266, (Rat) P21932, (Mouse) Q8VHH7
Entrez Gene ID: (Human) 109, (Rat) 64508, (Mouse) 104111
cAMP biosynthetic process
female meiotic division
sensory perception of smell
cyclic nucleotide biosynthetic process
intracellular signal transduction
renal water homeostasis
signal transduction
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
single fertilization
acrosome reaction
olfactory learning
cAMP-mediated signaling
sperm motility
activation of protein kinase A activity
cellular response to glucagon stimulus
cellular response to forskolin
response to stimulus
