Search Thermo Fisher Scientific
图: 1 / 3
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: agouti related protein; agouti related protein homolog; Agouti-related protein; orexigenic neuropeptide
基因别名: AGRP; AGRT; ART; ASIP2
UniProt ID: (Human) O00253, (Mouse) P56473
Entrez Gene ID: (Human) 181, (Mouse) 11604, (Rat) 25582
分子生物学功能: intercellular signal molecule