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Invitrogen
Agmatine Polyclonal Antibody
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Agmatine Antibody (PA5-119515) in ELISA
ELISA of Agmatine in 100 µL (coated at a concentration of 10 µg/mL) of Agmatine carrier protein conjugate. Detection range is 600 ng/mL down to 2.2 ng/mL (coated ligand detection range). Sample was incubated with polyclonal Agmatine antibody (Product # PA5-119515), followed by Rabbit IgG (HRP) with a dilution of 1:2000.
产品信息
PA5-119515
产品规格
种属反应
Chemical
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Agmatine.
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
靶标信息
Agmatine, a polyamine formed by the decarboxylation of the amino acid L-arginine, is known for its diverse biological roles in the mammalian body. It acts as a neurotransmitter and neuromodulator in the central nervous system, with evidence suggesting its involvement in neuroprotection, modulation of nitric oxide synthesis, and regulation of ion channels and receptors. Agmatine interacts with multiple molecular targets, including NMDA receptors and alpha 2-adrenergic receptors, influencing various physiological and pathophysiological processes. Its therapeutic potential has been investigated in contexts such as neurodegeneration, metabolic disorders, and psychiatric conditions. Additionally, agmatine functions as an agonist for the farnesoid X receptor (FXR), impacting gut microbiota metabolism and contributing to metabolic syndrome conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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