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Invitrogen
Alivin 1 Polyclonal Antibody
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Alivin 1 Antibody (PA5-113062) in ICC/IF
Immunocytochemichal analysis of Alivin 1 in A549 cells using a Polyclonal antibody (Product # PA5-113062) at a dilution of 1:266. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L). Cells were also counter-stained with DAPI.
产品信息
PA5-113062
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Amphoterin-induced protein 2 protein (420-522AA)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
A novel primary response gene, Alivin 1 (ali1), is an activity-dependent gene and promotes survival of neurons. Sequence analyses reveal that rat, mouse, and human Ali1 proteins contain seven leucine-rich repeats, one IgC2-like loop and a transmembrane domain, and display homology to Kek and Trk families. Results suggest that expression of ali1 promotes depolarization-dependent survival of the granule neuron. Mouse ali1 was mapped to a locus approximately 55.3 cM from the centromere on chromosome 15 that is syntenic to positional candidate loci for familial Alzheimer's disease type 5 and Parkinson's disease 8 on human chromosome 12.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: adhesion molecule with Ig-like domain 2; alivin 1; Alivin-1; AMIGO-2; AMIGO2; amigo2 {ECO:0000312|EMBL:AAO48951.1}; amphoterin induced gene 2; Amphoterin-induced protein 2; DEGA; differentially expressed in gastric adenocarcinoma; Differentially expressed in gastric adenocarcinomas; transmembrane protein AMIGO2
基因别名: ALI1; AMIGO-2; AMIGO2; DEGA
UniProt ID: (Human) Q86SJ2, (Rat) Q7TNJ4
Entrez Gene ID: (Human) 347902, (Rat) 300186
