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Invitrogen
Alix Polyclonal Antibody
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产品信息
PA5-95321
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E.coli-derived human ALIX recombinant protein (Position: A2-D330).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Human ALIX shares 96.7% and 95.2% amino acid (aa) sequence identity with mouse and rat ALIX, respectively.
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human HepG2 whole cell, human PANC-1 whole cell, rat liver tissue, rat RH35 whole cell, mouse liver tissue, mouse NIH/3T3 whole cell. IHC: rat liver tissue, huamn lung tissue, huamn oesophagus squama tissue, huamn placenta tissue, mouse intestine tissue. ICC/IF: T-47D cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
Apoptotic linked-gene-product 2 (ALG-2) interacting protein X (ALIX) is a conserved adaptor protein which is ubiquitously expressed. Alix was originally reported to play a role in apoptosis but has recently been shown to be involved in other cellular mechanisms including endosomal sorting, endocytosis, viral budding and actin cytoskeleton assembly.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ALG-2 interacting protein 1; ALG-2 interacting protein X; ALG-2-interacting protein 1; ALG-2-interacting protein X; Alg2-interacting protein 1; Alg2-interacting protein X; apoptosis-linked gene 2-interacting protein X; dopamine receptor interacting protein 4; E2F1-inducible protein; Eig2; Hp95; MGC17003; PDCD6-interacting protein; Programmed cell death 6-interacting protein
基因别名: AI480591; AIP1; ALIX; AW544830; C76364; DRIP4; Eig2; HP95; KIAA1375; mKIAA1375; PDCD6IP; RGD1561176
UniProt ID: (Human) Q8WUM4, (Rat) Q9QZA2, (Mouse) Q9QZN8
Entrez Gene ID: (Human) 10015, (Rat) 501083, (Mouse) 18571
cell separation after cytokinesis
apoptotic process
nucleus organization
mitotic metaphase plate congression
regulation of centrosome duplication
protein transport
viral life cycle
multivesicular body assembly
viral budding via host ESCRT complex
ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
regulation of mitotic spindle assembly
positive regulation of exosomal secretion
regulation of extracellular exosome assembly
positive regulation of extracellular exosome assembly
cell division
transport
cell cycle
