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Bethyl Laboratories
Alpha-4 Polyclonal Antibody
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Alpha-4 Antibody (A300-471A) in WB
Detection of Alpha 4 by western blot and immunoprecipitation. Samples: A. Whole cell lysate (50 µg) from Ramos (R), K-562 (K) and mouse NIH 3T3 (M) cells. B. Whole cell lysate (1 mg/IP; ¼ of IP reaction loaded/lane) from Ramos cells. Antibodies: Affinity purified rabbit anti-Alpha 4 antibody BL1846 (Product # A300-471A) used at 0.4 µg/mL (A) and 1 µg/mL (B) for WB and at 3 µg/mg lysate for IP. Alpha 4 was also immunoprecipitated by BL1845 (Product #A300-470A), but not by BL1844, which are affinity purified antibodies to upstream epitopes o... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
A300-471A
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 300 and the C-terminus (residue 339) of human Protein Phosphatase 2A, regulatory subunit alpha-4 (Immunoglobulin binding protein 1).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
tris citrate/phosphate, pH 7-8
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat
靶标信息
The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha 4; alpha4 phosphoprotein; B cell signal transduction molecule alpha 4; bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ); CD79a-binding protein 1; IGBP1; immunoglobulin (CD79A) binding protein 1; lymphocyte signal transduction molecule alpha 4; phosphoprotein, component, 52 kDa; protein alpha-4; protein phosphatase 2/4/6 regulatory subunit; protein phosphatase 2A, regulatory subunit alpha-4; renal carcinoma antigen NY-REN-16; unnamed protein product
基因别名: ALPHA-4; alpha4; IBP1; MRXS28; p52; Pc52; Tap42
UniProt ID: (Human) P78318, (Mouse) Q61249
Entrez Gene ID: (Human) 3476, (Mouse) 18518
negative regulation of transcription from RNA polymerase II promoter
signal transduction
regulation of signal transduction
TOR signaling
negative regulation of stress-activated MAPK cascade
response to tumor necrosis factor
intracellular signal transduction
regulation of microtubule-based movement
response to interleukin-1
positive regulation of dephosphorylation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of apoptotic signaling pathway
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