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Alpha-hemolysin (Atidortoxumab Biosimilar) Recombinant Human Monoclonal Antibody
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Alpha-hemolysin (Atidortoxumab Biosimilar) Antibody (MA5-42168) in SDS-PAGE
SDS-PAGE analysis of the recombinant Staphylococcus aureus alpha toxin, bi-component leukocidins protein expressed in CHO cells using a Alpha-hemolysin (Atidortoxumab Biosimilar) monoclonal antibody (Product # MA5-42168). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
产品信息
MA5-42168
产品规格
种属反应
Bacteria
宿主/亚型
Human
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Staphylococcus aureus alpha toxin, bi-component leukocidins
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2.16 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
Alpha-hemolysin, also known as Hla, is a protein encoded by the hla gene in Staphylococcus aureus, a common pathogenic bacterium. The hla gene is located on the chromosome of Staphylococcus aureus. Alpha-hemolysin is a beta-barrel pore-forming toxin that disrupts the plasma membranes of host cells by creating transmembrane pores, leading to cell lysis and death. It plays a critical role in S. aureus pathogenicity by destroying red blood cells (hemolysis), white blood cells, and epithelial cells, facilitating tissue infection and immune evasion. The structure of alpha-hemolysin consists of a heptameric pore formed by seven identical monomers, each contributing a beta-strand to the formation of the pore.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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