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Invitrogen
Alternariol Recombinant Mouse Monoclonal Antibody (2B9)
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Alternariol Antibody (MA566644) in SDS-PAGE
SDS-PAGE characterization of Alternariol under reducing conditions. Lane M: Protein marker (kDa); Lane AOH: Purified Alternariol Recombinant Monoclonal (Product # MA566644). Alternariol showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-363.
产品信息
MA566644
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2B9
抗原
Conjugate of AOH hapten and KLH.
偶联物
形式
Liquid
浓度
3.2 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Alternariol (AOH) is a toxic secondary metabolite produced by the Alternaria fungi, commonly found in various plant products, including fruits like mandarins, oranges, and berries. It is known for its genotoxic and mutagenic properties, which pose significant health risks. Alternariol functions by suppressing T cell proliferation and cytokine secretion, mildly promoting T cell apoptosis, thereby exhibiting anti-inflammatory activity. The molecular structure of alternariol includes a perylene quinone core, which contributes to its biological activity. The gene location and specific biosynthesis pathways of alternariol within the Alternaria species are still under investigation, with ongoing research focusing on its mechanism of action and potential therapeutic applications. Sensitive and selective analytical methods have been developed to detect alternariol in food products, highlighting its importance in food safety and public health.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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