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Description: Aminopeptidase P is a glycosyl-phosphatidylinositol (GPI) anchored membrane enzyme that is recognized by a monoclonal antibody designated JG12 that was raised against rat glomerular membrane protein fractions and labeled intensely microvessels of kidney and lung.
Applications Tested: Immunohistochemistry (Paraffin).
This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Aminoacylproline aminopeptidase; cytoplasmic aminopeptidase P; Cytosolic aminopeptidase P; OTTHUMP00000020457; OTTHUMP00000058856; sAmp; Soluble aminopeptidase P; X-Pro aminopeptidase 1; X-Pro aminopeptidase 1, soluble; X-prolyl aminopeptidase 1, soluble; Xaa-Pro aminopeptidase 1; xpnpep1 {ECO:0000312|RGD:621274}
基因别名: App; Xpnpep1
UniProt ID: (Rat) O54975
Entrez Gene ID: (Rat) 170751