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Invitrogen
Amylin Polyclonal Antibody
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产品信息
PA5-32261
产品规格
种属反应
Human
已发表种属
C. elegans,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide derived from N-terminus of human amylin peptide
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.6, with 1% BSA
内含物
0.1% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is pancreas tissue.
靶标信息
Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAPP; Insulinoma amyloid peptide; Islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin
基因别名: DAP; IAP; IAPP
UniProt ID: (Human) P10997
Entrez Gene ID: (Human) 3375
