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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Ankyrin G Antibodies

          Antibodies Inc

          Ankyrin-G Monoclonal Antibody (N106/20), FL594

          查看其他24个Ankyrin G抗体

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          Cite Ankyrin-G Monoclonal Antibody (N106/20), FL594

          产品信息

          75-187-FL594

          应用
          建议稀释比
          已发表文章

          免疫细胞化学 (ICC/IF)

          Assay-dependent
          -

          酶联免疫吸附实验 (ELISA)

          Assay-dependent
          -
          产品规格

          种属反应

          Human, Mouse, Non-human primate, Rat

          宿主/亚型

          Mouse / IgG1

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          N106/20

          抗原

          Fusion protein ~1000 amino acids of Ankyrin-G (accession number E9PE32) produced recombinantly in E. Coli.

          偶联物

          FL594 FL594 FL594
          • Unconjugated
          • FL490
          • FL550
          • FL650
          • Request custom conjugation

          激发/发射光谱

          594/615 nm

          形式

          Liquid

          浓度

          0.5 mg/mL

          纯化类型

          Protein A

          保存液

          PBS

          内含物

          0.09% sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Dry ice (international)

          产品详细信息

          For maximum recovery of product, centrifuge the vial prior to removing the cap.

          靶标信息

          Ankyrin-G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms, localized to axon initial segments and nodes of Ranvier. Ankyrin-G is also found at sites of epithelial cell-cell contact and in the intracellular membranes of some cells. Ankyrin-G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain. Ankyrin-G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: ANK-3; ankyrin 3 (G); ankyrin 3, epithelial; Ankyrin-3; Ankyrin-G; brain-specific ankyrin-G

          查看更多 收起

          基因别名: 2900054D09Rik; AI314020; ANK-3; ANK3; AnkG; Ankyrin-3; ANKYRIN-G; MRT37

          查看更多 收起

          UniProt ID: (Human) Q12955, (Rat) O70511, (Mouse) G5E8K5

          查看更多 收起

          Entrez Gene ID: (Human) 288, (Rat) 361833, (Mouse) 11735

          查看更多 收起

          功能
          structural constituent of cytoskeleton protein binding cytoskeletal protein binding cytoskeletal adaptor activity spectrin binding protein binding, bridging ion channel binding cadherin binding scaffold/adaptor protein
          参与通路
          mitotic cytokinesis ER to Golgi vesicle-mediated transport plasma membrane organization cytoskeletal anchoring at plasma membrane signal transduction axonogenesis axon guidance neuromuscular junction development positive regulation of gene expression positive regulation of cell communication by electrical coupling positive regulation of sodium ion transport magnesium ion homeostasis neuronal action potential positive regulation of homotypic cell-cell adhesion Golgi to plasma membrane protein transport regulation of potassium ion transport establishment of protein localization positive regulation of membrane potential cellular response to magnesium ion membrane assembly protein localization to plasma membrane maintenance of protein location in plasma membrane protein targeting to plasma membrane positive regulation of protein targeting to membrane positive regulation of membrane depolarization during cardiac muscle cell action potential negative regulation of delayed rectifier potassium channel activity positive regulation of sodium ion transmembrane transporter activity positive regulation of cation channel activity synapse organization positive regulation of action potential
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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