Antibodies Inc

Ankyrin-R/G Monoclonal Antibody (N388A/27)

查看其他5个Ankyrin 1/3抗体

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Ankyrin-R/G Monoclonal Antibody (N388A/27)

产品信息

75-415

应用
建议稀释比
已发表文章

免疫印迹 (WB)

Assay-dependent
-

免疫组化（冰冻） (IHC (F))

Assay-dependent
-

免疫细胞化学 (ICC/IF)

Assay-dependent
-

酶联免疫吸附实验 (ELISA)

Assay-dependent
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG2b

分类

Monoclonal

类型

Antibody

克隆号

N388A/27

抗原

Fusion protein amino acids 1-1881 (full-length) of human Ankyrin-R (accession number P16157) produced recombinantly in E. Coli.
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4

内含物

0.065% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Dry ice (international)

产品详细信息

For maximum recovery of product, centrifuge the vial prior to removing the cap.

靶标信息

Ankyrin 1 and Ankyrin 3 are members of the ankyrin family of proteins, which are crucial for the stability and functionality of the cellular membrane and the organization of membrane-associated proteins. Both Ankyrin 1 and Ankyrin 3 are integral to maintaining the structure and functionality of cellular membranes and have significant roles in health and disease.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: ANK-1; ANK-3; ankyrin 1, erythrocytic; ankyrin 1, erythroid; ankyrin 3 (G); ankyrin 3, epithelial; Ankyrin-1; Ankyrin-3; Ankyrin-G; Ankyrin-R; brain-specific ankyrin-G; Erythrocyte ankyrin; normoblastic anemia

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基因别名: 2900054D09Rik; AI314020; ANK; Ank-1; ANK-3; ANK1; ANK3; AnkG; Ankyrin-3; ANKYRIN-G; MRT37; nb; pale; SPH1; SPH2

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UniProt ID: (Human) P16157, (Human) Q12955, (Mouse) Q02357, (Rat) O70511, (Mouse) G5E8K5

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Entrez Gene ID: (Human) 286, (Human) 288, (Mouse) 11733, (Rat) 306570, (Rat) 361833, (Mouse) 11735

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功能
structural molecule activity structural constituent of cytoskeleton protein binding cytoskeletal adaptor activity enzyme binding spectrin binding ATPase binding cytoskeletal protein binding protein binding, bridging ion channel binding cadherin binding scaffold/adaptor protein
参与通路
exocytosis ER to Golgi vesicle-mediated transport cytoskeleton organization signal transduction positive regulation of organelle organization maintenance of epithelial cell apical/basal polarity protein targeting to plasma membrane mitotic cytokinesis plasma membrane organization cytoskeletal anchoring at plasma membrane axonogenesis axon guidance neuromuscular junction development positive regulation of gene expression positive regulation of cell communication by electrical coupling positive regulation of sodium ion transport magnesium ion homeostasis neuronal action potential positive regulation of homotypic cell-cell adhesion Golgi to plasma membrane protein transport regulation of potassium ion transport establishment of protein localization positive regulation of membrane potential cellular response to magnesium ion membrane assembly protein localization to plasma membrane maintenance of protein location in plasma membrane positive regulation of protein targeting to membrane positive regulation of membrane depolarization during cardiac muscle cell action potential negative regulation of delayed rectifier potassium channel activity positive regulation of sodium ion transmembrane transporter activity positive regulation of cation channel activity porphyrin-containing compound biosynthetic process monovalent inorganic cation transport erythrocyte development iron ion homeostasis synapse organization positive regulation of action potential
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