Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
Annexin A1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
21990-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Annexin A1 Fusion Protein Ag17273 (1-346 aa encoded by BC001275)
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MAMVSEFLK QAWFIENEEQ EYVQTVKSSK GGPGSAVSPY PTFNPSSDVA ALHKAIMVKG VDEATIIDIL TKRNNAQRQQ IKAAYLQETG KPLDETLKKA LTGHLEEVVL ALLKTPAQFD ADELRAAMKG LGTDEDTLIE ILASRTNKEI RDINRVYREE LKRDLAKDIT SDTSGDFRNA LLSLAKGDRS EDFGVNEDLA DSDARALYEA GERRKGTDVN VFNTILTTRS YPQLRRVFQK YTKYSKHDMN KVLDLELKGD IEKCLTAIVK CATSKPAFFA EKLHQAMKGV GTRHKALIRI MVSRSEIDMN DIKAFYQKMY GISLCQAILD ETKGDYEKIL VALCGGN (1-346 aa encoded by BC001275)
靶标信息
Annexin I belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ANAX1; Annexin 1 (p35) (Lipocortin 1); Annexin A1; Annexin I; annexin I (lipocortin I); Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; lipocortin 1; Lipocortin I; p35; Phospholipase A2 inhibitory protein; RP11-71A24.1
基因别名: Anx-1; Anx-A1; ANX1; ANXA1; C430014K04Rik; Lpc-1; LPC1; p35
UniProt ID: (Human) P04083, (Mouse) P10107, (Rat) P07150
Entrez Gene ID: (Human) 301, (Mouse) 16952, (Rat) 25380
single-stranded DNA binding
single-stranded RNA binding
helicase activity
receptor binding
structural molecule activity
calcium ion binding
protein binding
phospholipid binding
calcium-dependent phospholipid binding
phospholipase A2 inhibitor activity
protein binding, bridging
double-stranded DNA-dependent ATPase activity
annealing helicase activity
protein homodimerization activity
calcium-dependent protein binding
cadherin binding involved in cell-cell adhesion
phospholipase inhibitor activity
calcium-binding protein
DNA strand renaturation
neutrophil homeostasis
adaptive immune response
monocyte chemotaxis
regulation of leukocyte migration
phagocytosis
inflammatory response
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
regulation of cell shape
response to X-ray
myoblast migration involved in skeletal muscle regeneration
peptide cross-linking
insulin secretion
keratinocyte differentiation
prostate gland development
endocrine pancreas development
positive regulation of vesicle fusion
positive regulation of prostaglandin biosynthetic process
actin cytoskeleton reorganization
response to estradiol
DNA duplex unwinding
regulation of interleukin-1 production
positive regulation of interleukin-2 production
positive regulation of neutrophil apoptotic process
DNA rewinding
gliogenesis
positive regulation of T cell proliferation
response to drug
negative regulation of apoptotic process
response to peptide hormone
estrous cycle
innate immune response
positive regulation of T-helper 1 cell differentiation
negative regulation of T-helper 2 cell differentiation
negative regulation of exocytosis
alpha-beta T cell differentiation
regulation of hormone secretion
arachidonic acid secretion
regulation of inflammatory response
cellular response to hydrogen peroxide
hepatocyte differentiation
prolactin secretion
response to interleukin-1
cellular response to glucocorticoid stimulus
granulocyte chemotaxis
positive regulation of wound healing
neutrophil clearance
positive regulation of G1/S transition of mitotic cell cycle
negative regulation of phospholipase A2 activity
negative regulation of interleukin-8 secretion
regulation of cell proliferation
positive regulation of apoptotic process
negative regulation of protein secretion
response to hormone
response to organic cyclic compound
response to corticosteroid
response to glucocorticoid
