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Invitrogen
Annexin A1 Polyclonal Antibody
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Annexin A1 Antibody (PA5-19084) in IHC (P)
Immunohistochemistry analysis of Annexin A1 in human prostate. Samples were incubated with Annexin A1 polyclonal antibody (Product # PA5-19084) using a dilution of 4 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-19084
产品规格
种属反应
Human,
Mouse,
Pig,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (CQAILDETKGDYEK) corresponding to the C-terminus amino acids of ANXA1 (aa 324-337).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine and canine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.
靶标信息
Annexin I belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ANAX1; Annexin 1 (p35) (Lipocortin 1); Annexin A1; Annexin I; Annexin-1; ANX1; Calpactin II; Calpactin-2; Chromobindin-9; epididymis secretory sperm binding protein; lipocortin 1; Lipocortin I; LPC1; p35; Phospholipase A2 inhibitory protein; RP11-71A24.1
基因别名: Anx-1; Anx-A1; ANX1; ANXA1; C430014K04Rik; Lpc-1; Lpc1; p35
UniProt ID: (Pig) P19619, (Mouse) P10107, (Rat) P07150
Entrez Gene ID: (Pig) 396942, (Mouse) 16952, (Rat) 25380
calcium ion binding
calcium-dependent phospholipid binding
phospholipase A2 inhibitor activity
single-stranded DNA binding
single-stranded RNA binding
helicase activity
phospholipase inhibitor activity
structural molecule activity
protein binding
phospholipid binding
protein binding, bridging
double-stranded DNA-dependent ATPase activity
annealing helicase activity
protein homodimerization activity
calcium-dependent protein binding
calcium-binding protein
adaptive immune response
monocyte chemotaxis
regulation of leukocyte migration
phagocytosis
inflammatory response
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
regulation of cell shape
actin cytoskeleton reorganization
regulation of interleukin-1 production
positive regulation of interleukin-2 production
positive regulation of T cell proliferation
negative regulation of catalytic activity
innate immune response
positive regulation of T-helper 1 cell differentiation
negative regulation of T-helper 2 cell differentiation
negative regulation of exocytosis
regulation of hormone secretion
regulation of inflammatory response
cellular response to glucocorticoid stimulus
granulocyte chemotaxis
positive regulation of wound healing
DNA strand renaturation
neutrophil homeostasis
signal transduction
cell surface receptor signaling pathway
peptide cross-linking
insulin secretion
keratinocyte differentiation
positive regulation of vesicle fusion
positive regulation of prostaglandin biosynthetic process
DNA duplex unwinding
positive regulation of neutrophil apoptotic process
DNA rewinding
regulation of cell proliferation
positive regulation of apoptotic process
alpha-beta T cell differentiation
arachidonic acid secretion
negative regulation of protein secretion
cellular response to hydrogen peroxide
prolactin secretion
neutrophil clearance
positive regulation of G1/S transition of mitotic cell cycle
negative regulation of phospholipase A2 activity
negative regulation of interleukin-8 secretion
response to hormone
response to X-ray
response to organic cyclic compound
prostate gland development
endocrine pancreas development
response to corticosteroid
response to estradiol
gliogenesis
response to drug
response to peptide hormone
estrous cycle
response to glucocorticoid
hepatocyte differentiation
response to interleukin-1
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