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Invitrogen
Annexin A4 Polyclonal Antibody
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产品信息
PA5-78782
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human Annexin IV (7-21aa TVKAASGFNAMEDAQ).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5mg BSA
内含物
0.05mg sodium azide, 0.05mg thimerosal
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Caco-2 whole cell, human SiHa whole cell, human Hacat whole cell, human Hela whole cell, human U251 whole cell, human A549 whole cell, human PC-3 whole cell, rat lung tissue, mouse lung tissue. IHC: Human Mammary Cancer tissue, Rat Pancreas tissue.
靶标信息
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 35-beta calcimedin; 36 kDa zymogen granule membrane-associated protein; Annexin A4; Annexin IV; annexin IV (placental anticoagulant protein II); Annexin-4; ANXA 4; Carbohydrate-binding protein p33/p41; Chromobindin-4; Endonexin I; epididymis secretory protein Li 274; Lipocortin IV; P32.5; PAP-II; Placental anticoagulant protein II; PP4-X; proliferation-inducing gene 28; proliferation-inducing protein 28; Protein II; ZAP 36/annexin IV; ZAP36
基因别名: AI265406; AIV; ANX4; ANXA4; AW106930; HEL-S-274; P32.5; PAP-II; PIG28; PP4-X; Xanx-4; ZAP36
UniProt ID: (Human) P09525, (Mouse) Q3UCL0
Entrez Gene ID: (Human) 307, (Rat) 79124, (Mouse) 11746
regulation of transcription from RNA polymerase II promoter
signal transduction
Notch signaling pathway
epithelial cell differentiation
negative regulation of NF-kappaB transcription factor activity
negative regulation of apoptotic process
negative regulation of catalytic activity
negative regulation of interleukin-8 secretion
exocytosis
kidney development
