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Invitrogen
Apelin Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-51279
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide of human APLN
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.5 mg/mL
规格
150 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous levels of total Apelin protein.
靶标信息
This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AGTRL1 ligand; Apelin; apelin, AGTRL1 ligand; APJ endogenous ligand; preproapelin; unnamed protein product
基因别名: 6030430G11Rik; APEL; APLN; XNPEP2
UniProt ID: (Human) Q9ULZ1, (Mouse) Q9R0R4, (Rat) Q9R0R3
Entrez Gene ID: (Human) 8862, (Mouse) 30878, (Rat) 58812
regulation of the force of heart contraction
signal transduction
G-protein coupled receptor signaling pathway
feeding behavior
positive regulation of cell proliferation
positive regulation of heat generation
positive regulation of phosphorylation
drinking behavior
regulation of respiratory gaseous exchange
negative regulation of blood pressure
negative regulation of vasoconstriction
positive regulation of vasodilation
regulation of body fluid levels
positive regulation of corticotropin secretion
positive regulation of corticotropin-releasing hormone secretion
angiogenesis
G-protein coupled receptor internalization
negative regulation of systemic arterial blood pressure
immune response
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
gastrulation
lactation
positive regulation of heart rate
positive regulation of cardiac muscle hypertrophy
negative regulation of gene expression
negative regulation of fibroblast growth factor receptor signaling pathway
positive regulation of heart contraction
apelin receptor signaling pathway
coronary vasculature development
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of cardiac muscle hypertrophy in response to stress
positive regulation of cardiac muscle hypertrophy in response to stress
positive regulation of G protein-coupled receptor internalization
negative regulation of vascular smooth muscle cell proliferation
positive regulation of vascular endothelial cell proliferation
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
