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Invitrogen
ApoA1 Recombinant Rabbit Monoclonal Antibody (031)
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产品信息
MA5-30063
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
031
抗原
Recombinant Human Apolipoprotein A-I/ApoA1 Protein (Asp25-Gln267)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human Apolipoprotein A-I/ApoA1.
靶标信息
Apolipoprotein A-1 (apo A-1) in human plasma is a major protein component of high density lipoprotein (HDL). The molecular mass is 24 kDa. Apo A-1 is a cofactor for enzymes involved in the normal turnover of cholesterol and is produced in the liver. Plasma concentration is 270-380 mg/100 mL.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 1-Sep; 2-Sep; Apo a; apo A-1; APO A1; APO I; Apo-AI; ApoAI; Apolipoprotein; Apolipoprotein A-I; Apolipoprotein A1; Apolipoprotein AI; MGC102525; MGC117399; MGC124929; Udpgt; Ugt1; Ugt1a7
基因别名: apo(a); APOA1
UniProt ID: (Human) P02647
Entrez Gene ID: (Human) 335
beta-amyloid binding
protein binding
phospholipid binding
phospholipid transporter activity
high-density lipoprotein particle binding
cholesterol binding
cholesterol transporter activity
enzyme binding
phosphatidylcholine binding
apolipoprotein receptor binding
apolipoprotein A-I receptor binding
identical protein binding
chemorepellent activity
lipase inhibitor activity
phosphatidylcholine-sterol O-acyltransferase activator activity
high-density lipoprotein particle receptor binding
apolipoprotein
retinoid metabolic process
regulation of protein phosphorylation
endothelial cell proliferation
platelet degranulation
negative regulation of cytokine secretion involved in immune response
phospholipid metabolic process
phosphatidylcholine biosynthetic process
cholesterol biosynthetic process
receptor-mediated endocytosis
transforming growth factor beta receptor signaling pathway
G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
response to nutrient
cholesterol metabolic process
glucocorticoid metabolic process
negative regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
negative regulation of very-low-density lipoprotein particle remodeling
peripheral nervous system axon regeneration
protein oxidation
peptidyl-methionine modification
triglyceride catabolic process
lipid storage
regulation of intestinal cholesterol absorption
cholesterol transport
adrenal gland development
organ regeneration
neuron projection regeneration
regulation of Cdc42 protein signal transduction
cholesterol efflux
phospholipid efflux
negative regulation of heterotypic cell-cell adhesion
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
high-density lipoprotein particle clearance
positive regulation of Rho protein signal transduction
lipoprotein metabolic process
lipoprotein biosynthetic process
response to drug
cholesterol homeostasis
blood vessel endothelial cell migration
response to estrogen
reverse cholesterol transport
cellular protein metabolic process
positive regulation of fatty acid biosynthetic process
negative regulation of interleukin-1 beta secretion
negative regulation of inflammatory response
protein stabilization
negative chemotaxis
positive regulation of lipoprotein lipase activity
vitamin transport
positive regulation of hydrolase activity
positive regulation of stress fiber assembly
transmembrane transport
phospholipid homeostasis
negative regulation of lipase activity
negative regulation of cell adhesion molecule production
negative regulation of response to cytokine stimulus
triglyceride homeostasis
ERK1 and ERK2 cascade
cholesterol import
positive regulation of substrate adhesion-dependent cell spreading
