Bethyl Laboratories

ApoCIII Polyclonal Antibody

查看其他21个ApoC3抗体

问题与答案

问题与答案

产品信息

A81-117A

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:40,000

-

酶联免疫吸附实验 (ELISA)

1:1,000-1:40,000

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Human Apolipoprotein CIII.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

75mM sodium phosphate/PBS, pH 7.2, with 0.5mM EDTA

内含物

0.02% sodium azide

保存条件

4°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is a component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Apo-CIII; apoC-III; Apolipoprotein; Apolipoprotein C-III; Apolipoprotein C3; MGC150353

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基因别名: APOC3; APOCIII; HALP2

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UniProt ID: (Human) P02656

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Entrez Gene ID: (Human) 345

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phospholipid binding cholesterol binding enzyme regulator activity lipase inhibitor activity high-density lipoprotein particle receptor binding apolipoprotein

retinoid metabolic process triglyceride metabolic process inflammatory response G-protein coupled receptor signaling pathway positive regulation of triglyceride biosynthetic process negative regulation of triglyceride catabolic process negative regulation of very-low-density lipoprotein particle remodeling negative regulation of very-low-density lipoprotein particle clearance negative regulation of high-density lipoprotein particle clearance negative regulation of low-density lipoprotein particle clearance triglyceride catabolic process regulation of Cdc42 protein signal transduction response to vitamin A cholesterol efflux phospholipid efflux response to triglyceride high-density lipoprotein particle remodeling very-low-density lipoprotein particle assembly chylomicron remnant clearance lipoprotein metabolic process response to drug cholesterol homeostasis lipoprotein transport response to peptide hormone reverse cholesterol transport negative regulation of fatty acid biosynthetic process negative regulation of lipid metabolic process negative regulation of receptor-mediated endocytosis negative regulation of lipid catabolic process negative regulation of lipoprotein lipase activity negative regulation of cholesterol import triglyceride homeostasis response to fatty acid cellular response to glucose stimulus negative regulation of oxidative phosphorylation response to simvastatin