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Invitrogen
Apolipoprotein C2 Polyclonal Antibody
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产品信息
PA1-22561
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Apolipoprotein Type C-II produced synthetically in full-length form (not selected epitopes).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
BBS, pH 8, with 0.075M NaCl, 5mM EDTA
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages. The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: APC 2; APO C2; Apo CII; Apo-CII; APOC 2; ApoC II; APOC2 protein; ApoCII; Apolipoprotein C II; Apolipoprotein C-II; Apolipoprotein C2; Apolipoprotein CII; ApolipoproteinCII; MGC75082
基因别名: APC2; APO-CII; APOC-II; APOC2
UniProt ID: (Human) P02655
Entrez Gene ID: (Human) 344
retinoid metabolic process
positive regulation of phospholipase activity
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
negative regulation of very-low-density lipoprotein particle clearance
lipid catabolic process
negative regulation of cholesterol transport
cholesterol efflux
phospholipid efflux
triglyceride-rich lipoprotein particle remodeling
chylomicron remodeling
very-low-density lipoprotein particle remodeling
chylomicron remnant clearance
high-density lipoprotein particle clearance
lipoprotein metabolic process
cholesterol homeostasis
negative regulation of catalytic activity
reverse cholesterol transport
positive regulation of fatty acid biosynthetic process
negative regulation of lipid metabolic process
negative regulation of receptor-mediated endocytosis
positive regulation of lipoprotein lipase activity
positive regulation of phospholipid catabolic process
triglyceride homeostasis
