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Aquaporin 1 Polyclonal Antibody

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Aquaporin 1 Polyclonal Antibody

产品信息

600-401-E89

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:1,000-4,000
-

免疫组化（石蜡） (IHC (P))

Assay-dependent
-

免疫细胞化学 (ICC/IF)

1:200-1:400
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Aquaporin 1 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide corresponding to the N-terminal region of rat aquaporin 1.
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.2, with 50% glycerol

内含物

0.1% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 28 kda erythrocyte integral membrane protein homolog; AQP 1; AQP CHIP; AQP-1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; bloodgroup CO protein; Channel-like integral membrane protein of 28 kDa; channel-like integral membrane protein, 28-kDa; CHIP 28; Colton blood group; Colton blood group antigen; Delayed early response protein 2; DER2; growth factor-induced delayed early response protein; MGC26324; unnamed protein product; Urine water channel; water channel protein for red blood cells and kidney proximal tubule

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基因别名: AQP-CHIP; AQP1; CHIP28; CO

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UniProt ID: (Human) P29972, (Mouse) Q02013, (Rat) P29975

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Entrez Gene ID: (Human) 358, (Mouse) 11826, (Rat) 25240

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功能
intracellular cGMP activated cation channel activity potassium channel activity water transmembrane transporter activity protein binding ammonium transmembrane transporter activity potassium ion transmembrane transporter activity glycerol transmembrane transporter activity water channel activity channel activity transmembrane transporter activity nitric oxide transmembrane transporter activity carbon dioxide transmembrane transporter activity identical protein binding ephrin receptor binding hydrogen peroxide channel activity transporter activity glycerol channel activity transporter
参与通路
renal water homeostasis glomerular filtration renal water transport potassium ion transport water transport cell volume homeostasis hyperosmotic response cellular water homeostasis fibroblast migration positive regulation of fibroblast migration carbon dioxide transport glycerol transport cell migration sensory perception of pain cellular homeostasis cGMP-mediated signaling lateral ventricle development pancreatic juice secretion nitric oxide transport establishment or maintenance of actin cytoskeleton polarity secretion by cell cerebrospinal fluid secretion secretory granule organization cellular response to UV transepithelial water transport carbon dioxide transmembrane transport wound healing odontogenesis negative regulation of apoptotic process lipid digestion positive regulation of angiogenesis positive regulation of saliva secretion positive regulation of fibroblast proliferation camera-type eye morphogenesis defense response to Gram-negative bacterium multicellular organismal water homeostasis corticotropin secretion establishment of localization in cell transmembrane transport renal water absorption cellular response to hydrogen peroxide cellular response to mechanical stimulus cellular response to copper ion cellular response to mercury ion cellular response to retinoic acid cellular response to cAMP cellular response to hypoxia cellular response to salt stress cellular hyperosmotic response cellular response to dexamethasone stimulus cellular response to nitric oxide potassium ion transmembrane transport metanephric descending thin limb development metanephric proximal straight tubule development metanephric proximal convoluted tubule segment 2 development metanephric glomerulus vasculature development ammonium transmembrane transport hydrogen peroxide transmembrane transport cation transmembrane transport cGMP biosynthetic process transport positive regulation of lamellipodium assembly positive regulation of epithelial cell migration organic cation transport ammonium transport water homeostasis positive regulation of cell migration cellular response to stress carbohydrate transmembrane transport response to drug negative regulation of cysteine-type endopeptidase activity involved in apoptotic process cellular response to inorganic substance maintenance of symbiont-containing vacuole by host response to hormone hyperosmotic salinity response response to estrogen
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