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Positive control: Jurkat cell lysate, MCF7 cell lysate, SH-SY5Y cell lysate, HeLa cell lysate, human heart tissue, SH-SY5Y, rat spleen tissue lysate, rat liver tissue lysate, rat kidney tissue lysate, RAW264.7 cell lysate, NIH/3T3 cell lysate, C2C12 cell lysate.
Predicted band size: 45 kDa
Subcellular Location: Cytoplasm, cytoskeleton, Cell projection, Nucleus.
ARP2 (actin-related protein 2) is an ATP-binding component of the ARP2/3 complex - a multiprotein complex that mediates actin polymerization upon stimulation by the nucleation-promoting factor (NPF). The ARP2/3 complex mediates the formation of branched actin networks in the cytoplasm and provides the force for cell motility. The ARP2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Actin-like protein 2; Actin-related protein 2; ARP2 actin-related protein 2 homolog
基因别名: 4921510D23Rik; AA409782; ACTR2; ARP2; D6Ertd746e
UniProt ID: (Human) P61160, (Rat) Q5M7U6, (Mouse) P61161
Entrez Gene ID: (Human) 10097, (Rat) 289820, (Mouse) 66713
分子生物学功能: actin and actin related protein actin or actin-binding cytoskeletal protein cytoskeletal protein