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Invitrogen
Axonal Growth Cones Monoclonal Antibody (2G13)
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产品信息
MA1-80893
产品规格
种属反应
Chicken,
Mouse,
Rat
宿主/亚型
Mouse
/ IgM
分类
Monoclonal
类型
Antibody
克隆号
2G13
抗原
Embryonic chick tectal membranes.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
tissue culture supernatant with 5-10% FBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product does not require protein digestion pre-treatment of paraffin embedded sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin embedded sections.
Mouse anti Growth Cone antibody, clone 2G13 recognizes a protein originally termed 2G13P which is localized to growth cones.
靶标信息
This protein was originally termed 2G13P, which is localized to growth cones. Subsequent investigation has identified this protein to be 40S ribosomal protein SA, also known as 37 kDa laminin receptor precursor or Laminin receptor 1 (Baloui et al. 2004). 40S ribosomal protein SA is a 296 amino acid ~37kDa membrane, cytoplasmic and nuclear protein required for the assembly and/or stability of the 40S ribosomal subunit. In vertebrate evolution the molecule has acquired a secondary function as a laminin receptor (UniProt: P50890). In growth cones expression is notable particularly in filopodia and lamellipodia in developing rat CNS and embryonic neurons in culture (Stettler et al. 1999). 40S ribosomal protein SA interacts with the filamentous actin cytoskeleton and therefore may be involved in growth cone motility (Stettler et al. 1999).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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