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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
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This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases|This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion|Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung|Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes|A pseudogene of this gene has been identified on the X chromosome
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); B-raf; B-Raf proto-oncogene, serine/threonine kinase; B-RAF1; BRAF1; carboxypeptidase A1 (pancreatic); casein kinase I alpha S-like; caspase 1, apoptosis-related cysteine peptidase; CKI-alpha; CKI-alpha-like; class IVb beta tubulin; clock regulator kinase; CSNK1A1; cysteine protease; DNA ADP-ribosyltransferase PARP1; down-regulated in lung cancer; epididymis secretory sperm binding protein; epididymis secretory sperm binding protein Li 77p; G protein beta1/gamma2 subunit-interacting factor 1; H3 histone family, member A; HIST1H3A; histone 1, H3a; histone cluster 1 H3 family member a; histone cluster 1, H3a; histone H3/a; IL-1 beta-converting enzyme; IL1B-convertase; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; microtubule protein; microtubule-associated protein tau; NAD(+) ADP-ribosyltransferase 1; neurofibrillary tangle protein; NS7; paired helical filament-tau; pancreatic carboxypeptidase A; PHF-tau; poly (ADP-ribose) polymerase family, member 1; poly(ADP-ribose) polymerase; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; protein phosphatase 1, regulatory subunit 103; protein poly-ADP-ribosyltransferase PARP1; RAFB1; Tau-derived paired helical filament hexapeptide; tubulin beta-2 chain; tubulin beta-2C chain; tubulin, beta 2C; tubulin, beta, 2; unnamed protein product
基因别名: ADPRT; ADPRT 1; ADPRT1; ARTD1; Beta2; CK1; CK1a; CKIa; CPA; DDPAC; FTD1; FTDP-17; H3/A; H3FA; HEL-S-77p; HIST1H3A; HLCDGP1; ICE; IL1BC; LCAEOD; MAPTL; MSTD; MTBT1; MTBT2; P45; pADPRT-1; PARP; PARP-1; PARS; Poly-PARP; PPND; PPOL; PPP1R103; PRO2975; TAU; tau-40; Tau-PHF6; TUBB2; TUBB2C
UniProt ID: (Human) P29466, (Human) P15085, (Human) P48729, (Human) Q8N752, (Human) P68431, (Human) P10636, (Human) P09874, (Human) P68371
Entrez Gene ID: (Human) 834, (Human) 1357, (Human) 1452, (Human) 122011, (Human) 8350, (Human) 4137, (Human) 142, (Human) 10383