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GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: (N-acetylneuraminyl)-galactosylglucosylceramide; Beta-1,4 N-acetylgalactosaminyltransferase 1; beta1,4GalNAC-T; GalNAc-T; GM2/GD2 synthase; UDP-N-acetyl-alpha-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide-beta-1, 4-N-acetylgalactosaminyltransferase
基因别名: 4933429D13Rik; B4GALNT1; Gal-NAc-T; GALGT; Galgt1; GalNAc-T; GalNAcT; Ggm-2; Ggm2; SIAT2
UniProt ID: (Mouse) Q09200
Entrez Gene ID: (Mouse) 14421