Invitrogen

BAF53A Recombinant Rabbit Monoclonal Antibody (JU40-32)

Name: BAF53A Recombinant Rabbit Monoclonal Antibody (JU40-32)
Brand: Invitrogen
SKU: MA5-41247

查看其他21个BAF53A抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (6)

BAF53A Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 6

BAF53A Antibody (MA5-41247) in ICC/IF

Immunocytochemistry/Immunofluorescence analysis of BAF53A in PC-3M cells (green) using BAF53A Recombinant Monoclonal Antibody (Product # MA5-41247). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. The nuclear counter stain is DAPI (blue).

BAF53A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Immunogen image

Immunogen Image BAF53A Recombinant Rabbit Monoclonal Antibody (JU40-32)

产品信息

MA5-41247

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:100

免疫细胞化学 (ICC/IF)

1:50-1:100

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

JU40-32

抗原

Recombinant protein within Human ACTL6A aa 185-326

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2899000

产品详细信息

This product is predicted to work in Immunoprecipitation at a dilution of 1:10-1:50.

靶标信息

BAF53A is a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 53 kDa BRG1-associated factor A; actin-like 6; actin-like 6A; actin-like 6B; Actin-like protein 6A; actin-related protein 4; Actin-related protein Baf53a; ACTL6B; ArpNbeta; BAF complex 53 kDa subunit; BAF53; BAF53A; BAF53B; BRG1-associated factor 53A; BRG1/brm-associated factor 53A; hArpN alpha; hArpN beta; INO80 complex subunit K; MGC5382; MGC5382 Arp4

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基因别名: 2810432C06Rik; ACTL6; ACTL6A; AI851094; ARP4; ARPN-BETA; BAF53; BAF53A; C79802; INO80K

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UniProt ID: (Human) O96019, (Mouse) Q9Z2N8

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Entrez Gene ID: (Human) 86, (Mouse) 56456

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功能

RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding chromatin binding transcription coactivator activity protein binding nucleosomal DNA binding actin and actin related protein actin or actin-binding cytoskeletal protein cytoskeletal protein

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