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Invitrogen
BAF57 Polyclonal Antibody
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BAF57 Antibody (PA5-28421) in ICC/IF
BAF57 Polyclonal Antibody detects BAF57 protein at nucleus by immunofluorescent analysis. Sample: HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: BAF57 protein stained by BAF57 Polyclonal Antibody (Product # PA5-28421) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-28421
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human BAF57. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: Raji.
Predicted reactivity: Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BAF57; BRG1-associated factor 57; chromatin remodeling complex BRG1-associated factor 57; SMARCE 1; SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
基因别名: 2810417B20Rik; 5830412H02Rik; 9030408N19Rik; Baf27; BAF57; CSS5; SMARCE1
UniProt ID: (Human) Q969G3, (Mouse) O54941
Entrez Gene ID: (Human) 6605, (Mouse) 57376
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
chromatin binding
transcription coactivator activity
RNA binding
protein binding
N-acetyltransferase activity
ligand-dependent nuclear receptor binding
nucleosomal DNA binding
protein N-terminus binding
DNA binding
chromatin/chromatin-binding, or -regulatory protein
nucleosome disassembly
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
covalent chromatin modification
neurogenesis
ATP-dependent chromatin remodeling
negative regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
nervous system development
metabolic process
chromatin modification
