Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Bethyl Laboratories
BAF57/SMARCE1 Recombinant Rabbit Monoclonal Antibody (BLR316M)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
A700-316
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
BLR316M
抗原
Recombinant antibody was purified from cell culture supernatant. Immunogen was a peptide representing a region between residue 361 and the C-terminus (residue 411) of human BAF57/SMARCE1 using the numbering given in entry NP_003070.3 (Gene ID 6605).
偶联物
形式
Liquid
浓度
100 µg/mL
纯化类型
purified
保存液
PBS, pH 6.8-7.4, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: BAF57; BRG1-associated factor 57; chromatin remodeling complex BRG1-associated factor 57; SMARCE 1; SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1
基因别名: 2810417B20Rik; 5830412H02Rik; 9030408N19Rik; Baf27; BAF57; CSS5; SMARCE1
UniProt ID: (Human) Q969G3, (Mouse) O54941
Entrez Gene ID: (Human) 6605, (Mouse) 57376
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
chromatin binding
transcription coactivator activity
RNA binding
protein binding
N-acetyltransferase activity
ligand-dependent nuclear receptor binding
nucleosomal DNA binding
protein N-terminus binding
DNA binding
chromatin/chromatin-binding, or -regulatory protein
nucleosome disassembly
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
covalent chromatin modification
neurogenesis
ATP-dependent chromatin remodeling
negative regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
nervous system development
metabolic process
chromatin modification
