Search
Invitrogen
BAIAP2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 4
BAIAP2 Antibody (PA5-30386) in ICC/IF
Immunocytochemistry (Confocal immunofluorescence) of BAIAP2 in methanol-fixed A431. Samples were incubated with BAIAP2 polyclonal antibody (Product # PA5-30386) using a dilution of 1:500 (green). Alpha-tubulin filaments were labeled with alpha Tubulin monoclonal antibody (Product # MA1-25054) (Red) at 1:2,000.
产品信息
PA5-30386
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human BAIAP2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.7 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: SK-N-SH, mouse brain, rat brain.
Predicted reactivity: Mouse (98%), Rat (98%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: BAI-associated protein 2; BAI1 associated protein 2; BAI1-associated protein 2; BAR/IMD domain-containing adapter protein 2; Brain-specific angiogenesis inhibitor 1-associated protein 2; Fas ligand-associated factor 3; FLAF3; insulin receptor substrate 53; insulin receptor substrate of 53 kDa; insulin receptor substrate p53; Insulin receptor substrate p53/p58; Insulin receptor substrate protein of 53 kDa; Insulin receptor tyrosine kinase 53 kDa substrate; Insulin receptor tyrosine kinase substrate protein p53; IRS-58; IRSp53; IRSp53/58; unnamed protein product; WASP and MIM like
基因别名: BAIAP2; BAP2; FLAF3; IRSP53; R75030; WAML
UniProt ID: (Human) Q9UQB8, (Mouse) Q8BKX1, (Rat) Q6GMN2
Entrez Gene ID: (Human) 10458, (Mouse) 108100, (Rat) 117542
plasma membrane organization
axonogenesis
insulin receptor signaling pathway
regulation of cell shape
positive regulation of neuron projection development
dendrite development
neuron differentiation
positive regulation of actin filament polymerization
regulation of actin cytoskeleton organization
protein localization to synapse
regulation of synaptic plasticity
modulation of synaptic transmission
actin filament bundle assembly
actin crosslink formation
positive regulation of dendritic spine morphogenesis
cellular response to epidermal growth factor stimulus
cell-cell adhesion
regulation of postsynapse organization
cellular response to L-glutamate
regulation of modification of postsynaptic actin cytoskeleton
positive regulation of excitatory postsynaptic potential
Rho protein signal transduction
response to bacterium
positive regulation of actin cytoskeleton reorganization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
