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Abnova
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Sequence of this protein is as follows: YGTSPGQARE GSLTKGRPDV AKRLSLTMGG VQAREQNLPR GNLLRNKEKS GSQPACLDHM QDRRALSLKA HQSESYLPIG CKLPPQSSGV DTSPCPNSPV FRTGSEPA
Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48.
仅用于科研。不用于诊断过程。未经明确授权不得转售。