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Abnova
BCL9 Monoclonal Antibody (2D4)
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产品信息
H00000607-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
2D4
抗原
BCL9 (NP_004317, 1036 a.a. approximately 1135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: DDDSPPARSP NLPSMNNMPG MGINTQNPRI SGPNPVVPMP TLSPMGMTQP LSHSNQMPSP NAVGPNIPPH GVPMGPGLMS HNPIMGHGSQ EPPMVPQGRM
靶标信息
BCL9 is involved in signal transduction through the Wnt pathway. It promotes beta-catenin's transcriptional activity. BCL9 is associated with B-cell acute lymphoblastic leukemia. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: B-cell CLL/lymphoma 9 protein; B-cell lymphoma 9 protein; bcl-9; Protein legless homolog
基因别名: BCL9; LGS
UniProt ID: (Human) O00512
Entrez Gene ID: (Human) 607
myotube differentiation involved in skeletal muscle regeneration
regulation of transforming growth factor beta receptor signaling pathway
somatic stem cell population maintenance
skeletal muscle cell differentiation
positive regulation of transcription from RNA polymerase II promoter
canonical Wnt signaling pathway
beta-catenin-TCF complex assembly
