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Invitrogen
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Antibody detects endogenous levels of total BEX1/2.
BEX1/BEX2 belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. BEX1/BEX2 has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: brain expressed gene 1; brain expressed, X-linked 1; Brain-expressed X-linked protein 1; Brain-expressed X-linked protein 1 homolog; Brain-expressed X-linked protein 2; Brain-expressed X-linked protein 2 homolog; EG2RVC; expression gene 2 in rat visual cortex; hBex2; ovarian granulosa cell 13.0 kDa protein hGR74; Protein BEX1; Protein BEX2; protein hBex2; reduced expression 3; Reduced expression protein 3; REX-3
基因别名: AA407839; AL024066; AU018692; BEX1; BEX2; Bex4; DJ79P11.1; EG2RVC; HBEX2; HGR74-h; Rex3
UniProt ID: (Human) Q9HBH7, (Human) Q9BXY8, (Mouse) Q9R224, (Rat) Q3MKQ2, (Rat) Q3MKQ1, (Mouse) Q9WTZ8
Entrez Gene ID: (Human) 55859, (Human) 84707, (Mouse) 19716, (Rat) 501625, (Rat) 363498, (Mouse) 12069