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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: YVGTAPSGCI GGLGARVTRR ALGISSVFLQ GLRSSGLATV PAPGLERDHG AVEDLGGCLV EYMAKVHALE QVSQELETQL
Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 91%.
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 49 kDa cytoskeletal protein; Beaded filament structural protein 2; CP47; CP49; Lens fiber cell beaded filament protein CP 47; Lens fiber cell beaded filament protein CP 49; Lens intermediate filament-like light; LIFL-L; MGC142078; MGC142080; Phakinin
基因别名: BFSP2
Entrez Gene ID: (Human) 8419