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Invitrogen
BLOC1S2 Polyclonal Antibody
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BLOC1S2 Antibody (PA5-25452) in IHC (P)
Immunohistochemistry analysis of BLOC1S2 in formalin fixed and paraffin embedded human cervix carcinoma. Samples were incubated with BLOC1S2 polyclonal antibody (Product # PA5-25452) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
产品信息
PA5-25452
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 14-40 amino acids from the central region of human BLOC1S2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with non-human primate based on sequence homology.
靶标信息
BLOC1S2 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 11 kDa centrosome associated protein; biogenesis of lysosomal organelles complex-1, subunit 2; Biogenesis of lysosome-related organelles complex 1 subunit 2; biogenesis of lysosome-related organelles complex-1, subunit 2; biogenesis of lysosome-related organelles complex-1, subunit 2A; BLOC-1 subunit 2; centrosomal 10 kDa protein; centrosome protein oncogene; Centrosome-associated protein; RP11-316M21.4
基因别名: 2410089B13Rik; BLOC1S2; Bloc1s2a; BLOS2; BORCS2; CEAP; CEAP11
UniProt ID: (Human) Q6QNY1, (Mouse) Q9CWG9
Entrez Gene ID: (Human) 282991, (Mouse) 73689
anterograde axonal transport
positive regulation of cell proliferation
extrinsic apoptotic signaling pathway via death domain receptors
neuron projection development
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
anterograde synaptic vesicle transport
mitochondrial outer membrane permeabilization
lysosome localization
melanosome organization
platelet dense granule organization
