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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: LPPLVVQRESA EEAWGTEEAP APAPARSLLQ LRLAES
Highest antigen sequence identity to the following orthologs - mouse 84%, rat 84%.
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Biogenesis of lysosome-related organelles complex 1 subunit 3; BLOC-1 subunit 3
基因别名: BLOC1S3; BLOS3
Entrez Gene ID: (Human) 388552