Search
Invitrogen
BMI-1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 2
BMI-1 Antibody (PA5-23308) in IHC (P)
Immunohistochemical analysis of BMI-1 in formalin-fixed, paraffin-embedded human cervix tissue. Samples were incubated in BMI-1 polyclonal antibody (Product # PA5-23308) using a dilution of 5 µg/mL. Isotype control (top left) and this antibody (bottom left, right).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-23308
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A portion of amino acids 270-320 of human BMI1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; COMMD3; murine leukemia viral (bmi-1) oncogene homolog; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; Polycomb group RING finger protein 4; putative; RING finger protein 51; RP11-573G6.1
基因别名: AW546694; Bmi-1; BMI1; flvi-2/bmi-1; FLVI2/BMI1; PCGF4; RNF51
UniProt ID: (Mouse) P25916
Entrez Gene ID: (Human) 648, (Rat) 307151, (Mouse) 12151
negative regulation of transcription from RNA polymerase II promoter
skeletal system development
in utero embryonic development
DNA methylation
humoral immune response
brain development
regulation of gene expression
histone acetylation
histone ubiquitination
rostrocaudal neural tube patterning
hemopoiesis
positive regulation of B cell proliferation
positive regulation of immature T cell proliferation in thymus
somatic stem cell division
positive regulation of fibroblast proliferation
embryonic skeletal system morphogenesis
embryonic skeletal system development
regulation of catalytic activity
positive regulation of ubiquitin-protein transferase activity
cellular response to interleukin-1
cellular response to dexamethasone stimulus
negative regulation of apoptotic signaling pathway
transcription, DNA-templated
regulation of transcription, DNA-templated
cellular process
chromatin modification
hematopoietic stem cell homeostasis
chromatin remodeling
segment specification
heterochromatin assembly
negative regulation of gene expression, epigenetic
negative regulation of transcription, DNA-templated
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
