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Invitrogen
BMP-8B Polyclonal Antibody
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BMP-8B Antibody (PA5-77881) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of BMP-8B was performed in Mock and transfected 293T cells fixed in 4% paraformaldehyde at RT for 15 min. Green: BMP-8B Polyclonal Antibody (Product # PA5-77881) diluted at 1:2000. Blue: Hoechst 33342 staining. Scale bar = 10 µm.
产品信息
PA5-77881
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human BMP8b. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: U87-MG, SK-N-SH, IMR32, SK-N-AS, human BMP8B-transfected 293T, mouse brain
Predicted reactivity: Human (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
BMP-8B encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. BMP-8B may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMP; BMP-8; BMP-8B; Bone morphogenetic protein; bone morphogenetic protein 8 (osteogenic protein 2); Bone morphogenetic protein 8B; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)); MGC131757; OP-2; Osteogenic protein 2
基因别名: BMP8; BMP8B; OP2
UniProt ID: (Human) P34820
Entrez Gene ID: (Human) 656
