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Invitrogen
BMS1 Polyclonal Antibody
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BMS1 Antibody (PA5-90414) in WB
Western blot analysis of BMS1 in extracts of various cell lines. Samples were incubated with BMS1 Polyclonal antibody (Product # PA5-90414) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 15s.
产品信息
PA5-90414
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 600-900 of human BMS1 (NP_0555683)
偶联物
形式
Liquid
浓度
0.93 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LSAEEEDSEN EEAIRKKLSK PSQVSSGQKL GPQNFIDETS DIENLLKEEE DYKEENNDSK ETSGALKWKE DLSRKAAEAF LRQQQAAPNL RKLIYGTVTE DNEEEDDDTL EELGGLFRVN QPDRECKHKA DSLDCSRFLV EAPHDWDLEE VMNSIRDCFV TGKWEDDKDA AKVLAEDEEL YGDFEDLETG DVHKGKSGPN TQNEDIEKEV KEEIDPDEEE SAKKKHLDKK RKLKEMFDAE YDEGESTYFD DLKGEMQKQA QLNRAEFEDQ DDEARVQYEG FRPGMYVRIE IENVPCEFVQ N; Positive Samples: A-431, HeLa, HepG2, MCF7, Mouse liver, Rat liver; Cellular Location: Nucleus, nucleolus
靶标信息
BMS1 (Ribosome biogenesis protein BMS1 homolog) is a 1,282 amino acid protein encoded by the human gene BMS1. BMS1 is a nuclear protein that belongs to the BMS1/TSR1 family (BMS1 subfamily). BMS1 is believed to act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus. The 40S ribosomal subunit is an important member of the 80S ribosome complex, which also includes initiator tRNA and a 60S ribosomal subunit. The 80S ribosome is assembled by eukaryotic initiation factors (eIFs) at the initiation codon of mRNA in order to begin translation initiation. The joining of these ribosomal subunits requires eIF5B.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BMS1 homolog, ribosome assembly protein; BMS1 ribosome biogenesis factor; BMS1-like, ribosome assembly protein; Ribosome assembly protein BMS1 homolog; Ribosome biogenesis protein BMS1 homolog
基因别名: AA408648; ACC; AU020092; AU043373; BB007109; BC030906; BMS1; BMS1L; KIAA0187; mKIAA0187
UniProt ID: (Human) Q14692
Entrez Gene ID: (Human) 9790, (Mouse) 213895, (Rat) 362426
