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Invitrogen
BOK Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-120442
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BOK (NP_115904.1).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.79 mg/mL
规格
79 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: Mouse brain, Rat testis. The target is usually found in the following locations: Endoplasmic reticulum membrane, Golgi apparatus membrane, Single-pass membrane protein.
Immunogen sequence: MEVLRRSSVF AAEIMDAFDR SPTDKELVAQ AKALGREYVH ARLLRAGLSW SAPERAAPVP GRLAEVCAVL LRLGDELEMI RPSVYRNVAR QLHISLQSEP
靶标信息
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains and is a pro-apoptotic BCL-2 protein identified in the ovary.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: a member of Bcl-2 family; alternatively spliced variant; truncated BH3 domain; apoptosis activator Mtd; bcl-2-like protein 9; BCL2 family apoptosis regulator; BCL2 related ovarian killer; bcl2-L-9; BCL2-related ovarian killer; BOK, BCL2 family apoptosis regulator; hBOK; unnamed protein product
基因别名: BCL2L9; Bok-BH3; BOKL; matador; mtd
UniProt ID: (Human) Q9UMX3, (Mouse) O35425, (Rat) Q792S6
Entrez Gene ID: (Human) 666, (Mouse) 51800, (Rat) 29884
release of cytochrome c from mitochondria
apoptotic process
cellular component disassembly involved in execution phase of apoptosis
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
regulation of autophagy
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of neuron apoptotic process
oligodendrocyte differentiation
protein oligomerization
neuron apoptotic process
regulation of cytosolic calcium ion concentration
negative regulation of mitochondrial depolarization
transmembrane transport
negative regulation of necroptotic process
intrinsic apoptotic signaling pathway by p53 class mediator
response to cisplatin
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of execution phase of apoptosis
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
regulation of chorionic trophoblast cell proliferation
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of PERK-mediated unfolded protein response
regulation of granulosa cell apoptotic process
positive regulation of intrinsic apoptotic signaling pathway
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