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Invitrogen
BRAF35 Polyclonal Antibody
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Product Details
PA5-92209
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.32 mg/mL
Amount
32 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: HeLa, Jurkat, SKOV3, Mouse kidney, Mouse uterus; Cellular Location: Chromosome, Nucleus
Target Information
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 94 kDa B-raf protein; B-Raf proto-oncogene serine/threonine-protein kinase (p94); B-Raf serine/threonine-protein; BRCA2-associated factor 35; FLJ26127; high mobility group 20 B; high mobility group protein 20 B; HMG box-containing protein 20B; murine sarcoma viral (v-raf) oncogene homolog B1; p94; Proto-oncogene B-Raf; serine/threonine protein kinase; Serine/threonine-protein kinase B-raf; SMARCE1-related protein; Structural DNA-binding protein BRAF35; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related; v-raf murine sarcoma viral oncogene homolog B; v-Raf murine sarcoma viral oncogene homolog B1
Gene Aliases: 9930012E13Rik; AA120551; AA387315; AA473386; AW610687; B-raf; B-RAF1; BRAF; BRAF-1; Braf-2; BRAF1; Braf2; BRAF35; C230098H17; C87398; D6Ertd631e; Hmg20b; Hmgx2; Hmgxb2; NS7; RAFB1; Smarce1r
UniProt ID: (Mouse) P28028, (Mouse) Q9Z104
Entrez Gene ID: (Human) 673, (Mouse) 109880, (Mouse) 15353
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
small GTPase binding
identical protein binding
scaffold protein binding
protein serine kinase activity
nucleotide binding
receptor signaling protein activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
mitogen-activated protein kinase kinase binding
metal ion binding
protein heterodimerization activity
four-way junction DNA binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
non-receptor serine/threonine protein kinase
MAPK cascade
protein phosphorylation
signal transduction
epidermal growth factor receptor signaling pathway
organ morphogenesis
positive regulation of gene expression
positive regulation of glucose transport
positive regulation of peptidyl-serine phosphorylation
negative regulation of apoptotic process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
establishment of protein localization to membrane
postsynaptic modulation of chemical synaptic transmission
activation of MAPKK activity
myeloid progenitor cell differentiation
visual learning
negative regulation of fibroblast migration
glucose transport
phosphorylation
cell differentiation
somatic stem cell population maintenance
intracellular signal transduction
cellular response to drug
regulation of cell proliferation
CD4-positive, alpha-beta T cell differentiation
positive T cell selection
response to peptide hormone
negative regulation of neuron apoptotic process
alpha-beta T cell differentiation
regulation of axon regeneration
positive regulation of axon regeneration
positive regulation of axonogenesis
protein heterooligomerization
positive regulation of stress fiber assembly
response to cAMP
long-term synaptic potentiation
head morphogenesis
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of synaptic vesicle exocytosis
negative regulation of endothelial cell apoptotic process
chromatin organization
chromatin remodeling
transcription, DNA-templated
regulation of transcription, DNA-templated
cell cycle
chromatin modification
negative regulation of protein sumoylation
skeletal muscle cell differentiation
positive regulation of neuron differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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