Search
Invitrogen
BRCA2 Monoclonal Antibody (234403)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 2
BRCA2 Antibody (MA5-23942) in IHC (P)
BRCA2 in Human Breast Cancer Tissue. BRCA2 was detected in immersion fixed paraffin-embedded sections of human breast cancer tissue using BRCA2 Monoclonal Antibody (Product # MA5-23942) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Mouse IgG HRP Antibody. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval. Tissue was stained u... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-23942
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
234403
抗原
E. coli-derived recombinant human BRCA2 Met1-Thr200
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects endogenous human BRCA2.
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
Breast Cancer Type 2 susceptibility protein (BRCA2) is a tumor-suppressor protein reported to be involved in double-strand break repair, homologous recombination and S-phase checkpoint activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: brca 2; brca-2; BRCA1/BRCA2-containing complex, subunit 2; BRCA2 DNA repair associated protein; breast and ovarian cancer susceptibility gene, early onset; breast and ovarian cancer susceptibility protein 2; breast cancer 2 tumor suppressor; breast cancer 2, early onset; DNA repair associated; DNA repair-associated BRCA2; FANCB; Fanconi anemia group D1 protein; mutant BRCA2; mutant DNA repair-associated protein 2; RP11-298P3.4; transcript variant 1
基因别名: BRCC2; BROVCA2; FACD; FAD; FAD1; FANCD; FANCD1; GLM3; PNCA2; XRCC11
UniProt ID: (Human) P51587
Entrez Gene ID: (Human) 675
telomere maintenance via recombination
double-strand break repair via homologous recombination
DNA recombinase assembly
DNA repair
nucleotide-excision repair
double-strand break repair
DNA recombination
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
male meiosis I
negative regulation of mammary gland epithelial cell proliferation
positive regulation of transcription, DNA-templated
centrosome duplication
establishment of protein localization to telomere
cellular response to ionizing radiation
mitotic recombination-dependent replication fork processing
double-strand break repair involved in meiotic recombination
regulation of DNA damage checkpoint
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
