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Invitrogen
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Antibody detects endogenous levels of total BRI3.
BRI3 (brain protein I3), also known as pRGR2 or I3, is a 125 amino acid multi-pass membrane protein. The gene that encodes BRI3 maps to human chromosome 7, which is about 158 milllion bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Brain protein I3; Membrane protein BRI3; pRGR2
基因别名: BRI3; I3
UniProt ID: (Human) O95415, (Rat) Q5PPK1, (Mouse) P28662
Entrez Gene ID: (Human) 25798, (Rat) 304284, (Mouse) 55950