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Abnova
BRPF1 Polyclonal Antibody, MaxPab™
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产品信息
H00007862-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
BRPF1 (NP_001003694.1, 1 a.a. approximately 1220 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNLDVVS EDEEAPEEAP ENGSNKENTE TPAATPKSGK HKNKEKRKDS NHHHHHNVSA STTPKLPEVV YRELEQDTPD APPRPTSYYR YIEKSAEELD EEVEYDMDEE DYIWLDIMNE RRKTEGVSPI PQEIFEYLMD RLEKESYFES HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV HQECYGVPYI PEGQWLCRRC LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV CFANTVFLEP IDSIEHIPPA RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY MKMEPVRETG ANGTSFSVRK TAYCDIHTPP GSARRLPALS HSEGEEDEDE EEDEGKGWSS EKVKKAKAKS RIKMKKARKI LAEKRAAAPV VSVPCIPPHR LSKITNRLTI QRKSQFMQRL HSYWTLKRQS RNGVPLLRRL QTHLQSQRNC DQVGRDSEDK NWALKEQLKS WQRLRHDLER ARLLVELIRK REKLKRETIK VQQIAMEMQL TPFLILLRKT LEQLQEKDTG NIFSEPVPLS EVTELDEVPD YLDHIKKPMD FFTMKQNLEA YRYLNFDDFE EDFNLIVSNC LKYNAKDTIF YRAAVRLREQ GGAVLRQARR QAEKMGIDFE TGMHIPHSLA GDEATHHTED AAEEERLVLL ENQKHLPVEE QLKLLLERLD EVNASKQSVG RSRRAKMIKK EMTALRRKLA HQRETGRDGP ERHGPSSRGS LTPHPAACDK DGQTDSAAEE SSSQETSKGL GPNMSSTPAH EVGRRTSVLF SKKNPKTAGP PKRPGRPPKN RESQMTPSHG GSPVGPPQLP IMSSLRQRKR GRSPRPSSSS DSDSDKSTED PPMDLPANGF SGGNQPVKKS FLVYRNDCSL PRSSSDSESS SSSSSSAASD RTSTTPSKQG RGKPSFSRGT FPEDSSEDTS GTENEAYSVG TGRGVGHSMV RKSLGRGAGW LSEDEDSPLD ALDLVWAKCR GYPSYPALII DPKMPREGMF HHGVPIPVPP LEVLKLGEQM TQEAREHLYL VLFFDNKRTW QWLPRTKLVP LGVNQDLDKE KMLEGRKSNI RKSVQIAYHR ALQHRSKVQG EQSSETSDSD
靶标信息
BRPF1 (peregrin) is a component of the MOZ/MORF complex. This complex has histone H3 acetyltransferase activity. BRPF1 preferentially mediates histone H3-K23 acetylation and positively regulates the transcription of RUNX1 and RUNX2. Mutations affecting the gene can result in intellectual developmental disorder with dysmorphic facies and ptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bromodomain and PHD finger-containing protein 1; bromodomain-containing protein, 140kD; Peregrin; Protein Br140
基因别名: BR140; BRPF1
UniProt ID: (Human) P55201
Entrez Gene ID: (Human) 7862
