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Invitrogen
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Immunogen sequence: SDNGINRLSL MAPDTPAGTP LSGVGRRTSV LFKKAKNGVK LQRSPDRVLE NGEDHGVAGS PASPASIEEE RHSRKRPRSR SCSESEGERS PQQEEETGMT NGFGKHTESG SDSECSLGLS GGLAFEACSG LTPPKRSRG
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 82%.
Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity (PubMed:16387653, PubMed:26620551, PubMed:26677226). Plays a role in DNA replication initiation by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby facilitating the activation of replication origins (PubMed:26620551). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:16387653). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bromodomain and PHD finger containing, 3; Bromodomain and PHD finger-containing protein 3
基因别名: BRPF3; KIAA1286
UniProt ID: (Human) Q9ULD4
Entrez Gene ID: (Human) 27154